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    • What humans can personally learn from Ants?
    • Repeated Disappointments
    • The meaning of happiness
    • Do I trust my senses?
    • Chemical Bonding >
      • An introduction
      • Topic 1 - Relationship with Allah
      • Topic 2 - Relationship with our fathers
      • Topic 3 - Relationship with our mothers
      • Topic 4 - Relationship with the spouses
      • Topic 5 - Relationship with Siblings
      • Topic 6: Relationship with Grandparents
    • Allah my sole companion
    • Old is Gold
    • The Man with the Lion's heart
    • Khadija radia allahu anha
    • Maryam - a source of inspiration
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  • Medicine and Health
    • MONDAY WEEKLY HEALTH SHOW
    • Friday Inspirations: Life Lessons Through Anatomy >
      • Take care of your heart
      • Do not carry the worries of life but the tools to make a positive change in it.
      • Free your mind and control your emotions
      • Take the good from every situation
      • Digest and Absorb knowledge
      • Filter your contacts
      • Sweet and Sour
      • The tongue that can bring Peace and War
      • My corrected vision
      • Are you hearing or are you listening?
    • What is cancer and its types?
    • Healthcare Publications >
      • The Eye Issue 13
      • The food journey
      • Diagnosis and Treatment of cancer
    • Lifestyle >
      • Maintaining Healthy Lifestyle
      • Nutrition and Exercise >
        • Drinking Water
        • Benefits of Avocado
        • Benefits of Honey
        • Benefits of Blackseed oil
        • Cancer >
          • Biology of Cancer >
            • Introduction to DNA
            • What are viruses?
            • Why viruses are replicated?
            • Herpes Virus
            • Viruses and Cancer
            • Vaccines
            • Penicllium and Pseudomona bacteria
            • Adaptive Immune Response
            • Innate Immune Response
          • Types of Cancer >
            • Breast Cancer
            • Prostate Cancer
            • Malignant Melanoma and Obesity
            • Neurological Tumours
          • Cancer Treatment >
            • Chemotherapy: A Introduction
        • Swimming: A sunnah issue 15
        • Yoga
        • A Good Health Makes You Rich
    • Respiratory >
      • Introduction to lungs
      • Asthma
    • The Bone and Muscles >
      • Cystic Fibrosis
      • Duchenne Muscular Dystrophy
      • Lower Back Pain
      • Neck Pain
      • Arthiritis
      • Comfort during pregnancy
    • The Heart and the Blood >
      • Heart Physiology
      • Coronary Heart Disease
      • Thrombocytopenia and its diagnosis
      • Haemolytic anaemia and its diagnosis
    • Diabetes Inspidus
    • Medicine and Islam >
      • The link between Medicine and Science with Glorious Quran >
        • Introduction
        • Embryology and the human development
        • The Power of Human Senses
        • The Brain - The Human Body's Main Processor
        • The wonders of the heart anatomy and physiology
        • The Conceptual Art of The Bone
        • The extraordinary tubular network of the small intestine and the conclusion of the research project
      • Medicine Through Islamic History
      • Healthy Wealthy tips for Ramadan
      • Prophetic Medicine
      • Ruqyah
      • Healing through Ruqya
      • Hajj and Eclipse >
        • Hajj and Health
        • Solar Eclipse
      • Spiritual Detox, Supplications and Recommended Reading
  • Spiritual Development
    • Standing up with purpose
    • Youtube Reminders
    • Quran - My Source of Solace
    • Tafseer Surah Al Fatihah
    • Temporary magnetic attraction
    • The Art of Dua
    • Remaining Faithful
    • Controlling Anger
    • My relationship with the Quran
    • Tawakkul
    • Everlasting love with Allah
    • My father who inspired me to do dawah,
  • Community Matters
    • Where is the Ummah?
    • Doses of Inspiration >
      • The importance of Amanah
      • Preparation for the Inevitable Hereafter
      • Are muslim women oppressed?
      • My thoughts on evolution
    • Giving charity and the fitnah of wealth
    • Depression in society
    • Reflection on Racism
    • A Muslimah's Identity
    • Teaching Children to Pray
    • Loving people for the sake of Allah
    • Connecting with sisters
    • Poem on sisterly love
  • Magnetic Love With Ramadan
    • Self-analysis and preparation of Ramadan
    • Poem on Ramadan
    • Mannerism Whilst Fasting
    • Reconnecting with Ramadan 2015
    • Season 1
    • Season 2
    • Season 3
    • Season 4 >
      • Part 1 Reminiscing how the Sahaba spent Ramadan
      • Part 2 Polishing Our Character
      • Part 3: Steadfastness after Ramadan
    • Season 5 >
      • The faith of Ibrahim
      • Pearls of Ramadan
      • Inspiring individuals from world history
      • The perserverance of Asiyah
    • Season 6 >
      • Pre-Ramadan Reminders
      • Daily Ramadan boost
      • Ramadan events
    • Season 7 >
      • Cementing our Purpose during COVID-19
      • Health and Well-being
    • Season 8
    • Season 9
    • Special addition to Season 9 Post- Fajr Reflections
    • Growth Through Ramadan
    • Season 10
  • Personal Motivational Quotes
    • Monday Motivation Season 1
    • General Daily Motivation Season 2
    • Opportunities to fast
    • Friday reminders
    • Lessons from Surah Kahf
    • *NEW* Sunday moments
  • Spoken Word Poetry
    • Themes >
      • Black History Month: Actions Not Words
      • Developing Yourself
      • Relationship with Allah
      • Character
      • Preparation for the Akhirah
      • Parents
      • Friendship
      • Humanity and Society
      • Reflections
      • Nature and Weather
      • Marriage and my amazing husband
  • Art
    • SUMMER FUN The Holy Land for Kids Colouring book!
    • Islamic Calligraphy
    • Customised names - Arabic Calligraphy
    • Special Occasions
    • Nature
    • Crafts: Home decor ideas
    • Crafts: Jewellery design
  • History
    • The Revival of Our Sacred Landmarks
    • History Podcasts
    • The magnitude of Islamic History
    • An insight to the Islamic Art of the Abbasid dynasty
    • April Fools Day
    • The Eminent Companions of Prophet salla allahu allayhi wa salam Season 1 >
      • Lessons of the Father of Kittens Abu Hurayrah (RA)
      • The pure faith of Ramla bint Abi Sufyan (RA)
      • A man of honour and dignity - Zubair Ibn Al Awam (RA)
      • Zaid ibn Harith - the beloved one (RA)
      • Julaybib (RA)
      • The Custodian of the Ummah - Abu Ubaydah ibn Jarrah
      • The man of paradise Bilal (RA)
      • Dhun Noorayn Uthman ibn Affan (RA)
      • Wisdom of Rumaysah bint Milhan (R
    • *Season 2 - NEW* The Eminent Companions of Prophet salla allahu allayhi wa salam >
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      • The Bravery of Saad ibn Muadh
      • Consistency of Bara ibn Azib RA
      • The courage of Fatima bint Asad
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    • Zahra Makeen
    • Jamila Jones
    • Tasnim Arbee
    • Asqarini Hasbi
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    • Suleiman Athman >
      • The Quest of Salvation Part 1 of 3 sequel
      • The Quest of Salvation Part II of 3
      • The Quest of Salvation Part 3 of 3
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  Welcome

Thrombocytopenia and its diagnosis

3/31/2015

1 Comment

 
Thrombocytopenia is a platelet count that is under the normal lower limit (150 x 109/L). Platelets otherwise known as thrombocytes are located in the blood alongside red blood cells (erythrocytes), white blood cells (leukocytes) and plasma. The megakaryocytes are large cells that develop in bone marrow and undergo fragmentation to produce platelets. Platelets have no nucleus, instead they have granules where proteins are located to assist with its function. The function of platelets is to help with blood clotting. Platelets ‘stick’ together to stop the blood flowing from damaged blood vessels.

This can be due to a number of causes:

1)     Platelet function abnormalities:
Thrombocytopathy – this can be due to defects such as genetics (inherited) and acquired of platelet function. Examples include Megakaryocytic hypoplasia – This is where megakaryocytes are underdeveloped,  
Wiskott-Aldrich syndrome (WAS) – This is an X-linked recessive disease.

2)     Low platelet production. 
This can be due to disorders of bone marrow due to a number of reasons:
Cancer: myeloma, leukaemia, lymphoma – It can also be caused by chemotherapy!
Infection – mainly viruses such as HIV, hepatitis, Epstein-Barr, Cytomegalovirus, Herpes Simplex, Varicella-Zoster.

3)     Low Platelet survival. This can be caused by:
Immune
This includes rheumatoid arthiritis, post-transfusion thrombocytopenic purpura (PTTP), neonatal alloimmune thrombocytopenia (NAIT).
PTTP: This is where antigens on transfused platelets, destruct transfused platelets as well as the platelets of the patients. This normally occurs 10 days after transfusion and can last few weeks.
NAIT: This is where the mother makes antibodies that are against the foetus (baby’s) platelets with paternal antigens. This can lead to severe neonatal thrombocytopenia.

Drug-Induced
Medications such as ibuprofen, vancomycin, heparin can cause thrombocytopenia.

Pregnancy. 
In some pregnancies, HELLP syndrome can occur and stands for:
·         Haemolysis.
·         EL (elevated liver) enzymes.
·         LP (low platelet) count.

4)     Dilutional thrombocytopenia
This is caused by transfusion of high volumes of blood that may have dead platelets.


Below is a diagnostic approach I created for thrombocytopenia and what tests recommended:

1 Comment
Toms Recipes link
10/15/2021 12:32:39 am

Great blogg I enjoyed reading

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